Sm-a-actin

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August undefined, 2024

Webb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . WebbSM a-actin promoter is regulated through combinatorial interactions between different factors. Transforming growth factor-b induced activity of the 125-bp rat SM a-actin promoter is dependent on both an intact transforming growth factor-bcontrol element and intact CArG boxes.18 Addition-ally, the homeodomain factor MHox activates SM a-actin

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Webb7 okt. 2024 · At E16.5, the expression of SM α-actin cannot detect in both control group and L-NAME treated group (Data not shown). At E17.5, SM α-actin expression observed in large vessels, as well as within ... Webbalpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of … mary poppins disneyland paris

Actin, alpha-Smooth Muscle monoclonal antibody Sma Antibody

WebbSee all alpha smooth muscle Actin primary antibodies Description Mouse monoclonal [1A4] to alpha smooth muscle Actin Host species Mouse Tested applications Suitable … Webb5 juni 1999 · In this study, the presence of a contractile actin isoform, alpha-smooth muscle (alpha-SM) actin, was assessed by immunohistochemistry in normal calf meniscal tissue and in meniscal cells in 2- and 3-dimensional culture. Calf meniscus cells were seeded in type I and type II collagen-glycosaminoglycan (GAG) matrices. WebbSM a-actin, SM myosin heavy chain (MHC), and h1 calponin. However, induction of SM a-actin by TGF-bis not restricted to SMCs. A study by Shah et al4 demonstrated that TGF-b stimulated differentiation of neural crest cells into SMCs or SMC-like cells based on morphological criteria and the induction of SM a-actin and h1 calponin. Of particular hutchens and hutchens law firm

SM a -actin – positive TSC2-null lesions show mTORC1 activation ...

Anti-alpha smooth muscle Actin antibody [1A4] (ab7817)

WebbThe antibody (also known as anti-α-Sm-1) is specific for the single isoform of α-smooth muscle actin. It reacts specifically with α-smooth muscle actin in immunoblotting … WebbAntibody 1A4 (DAKO) recognizes SM a-actin and was used to detect SMCs, whereas antibody HAM56 (DAKO) was used to recognize macrophages in the sections. Activin was detected with monoclonal antibody E4 (Serotec), and follistatin with an anti-peptide antibody (provided by Prof S. Werner, ETH, Zurich, Swit-zerland). mary poppins dress hot topicWebb3 dec. 2007 · We identified 2 types of migrating cells with distinctive actin filament structures at the migrating front: type I (Figure (Figure5A), 5 A), cells with a large amount of F-actin stress fibers forming lamellum-like protrusions, and type II (Figure (Figure5A), 5 A), cells with a polarized morphology, a ruffling lamellipodium at the leading edge facing the … mary poppins disney musicals

"Webb1 jan. 2008 · Alpha-smooth muscle actin (alpha-SMA) is the actin isoform that predominates within vascular smooth-muscle cells and plays an … " - Sm-a-actin

Sm-a-actin

WebbTransforming growth factor (TGF)-b-induced expression of smooth muscle (SM)-a-actin is accompanied by expression and activation of serum response factor (SRF). (A) Human … Webba decrease in expression of SM-a-actin and increases in non-muscle b-actin expression (5). It is presumed that modulation of VSMC phenotype is me-diated through activation of specific signal transduction path-ways that act on transcription factors. In cultured VSMC, increases in SM-a-actin expression are observed in response to specific agonists.

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Webbimmunocytochemical analysis using antibodies specific for either SM a-actin (Skalli et al., 1986) or SM myosin heavy chain (Kawamoto and Adelstein, 1987). Microscopic evaluation of a number of fields failed to uncover SM a-actin- or SM myosin heavy chain-negative cells (data not shown). Additionally, the expression of SM a-actin in WebbSmooth muscle alpha-actin (αSMA) is the definitive marker for the activated cardiac fibroblast population known as the myofibroblast (Frangogiannis et al., 2000), but this …

Webb9 maj 2012 · SM-α actin是平滑肌细胞抗体 Actin即“肌动蛋白”，是细胞的一种重要骨架蛋白。同时Actin在细胞分泌、吞噬、 β-Actin 移动、胞质流动和胞质分离等过程中起重要作 … Webb24 juni 2024 · Actin is a 43000 kDa ubiquitous protein found in all cells Actins are involved in cell motility (alpha, smooth muscle) and the maintenance of the cytoskeleton (beta and gamma, all cells) Antibodies …

WebbAlpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also … Webb30 maj 2024 · Western blot results showed that the expression of SM-a-actin and SM-22a was increased, whereas the expression of MMP-2 and TNF-α was decreased in VSMCs treated with 3-MA, in relative to shear stress group (Fig. 4), suggesting that the induction of autophagy could partially block the phenotypic transition of VSMCs.

Webb9 apr. 2024 · Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. Greve JN, et al. Eur J Cell Biol, 2024 Apr. PMID 35313204. A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers.

WebbThe Actin Alpha 2 (ACTA2) gene encoding smooth muscle aortic actin, was isolated and characterized. It was found that the ACTA2 gene contains at least 9 exons (7). Alpha smooth muscle actin appears to play an important functional role in myofibroblast contraction and migration. hutchens cleaners \u0026 laundry mount airy ncWebbin Sm-a-actin content with increasing age were due, in part, to an increase in Sm-a-actin synthesis. However, in SMCs from 90- and 180-day-old rats, the fractional content of Sm-a-actin exceeded its fractional synthesis at a time when total Sm-a-actin content was increas- ing. This suggests that Sm-a-actin turns over more slowly in mature animals. hutchens chevrolet newport newsWebbThermo Fisher nonmuscle beta actin emdb emd 27572 arora as huang hl heissler sm chinthalapudi k 2024 cryo em structure Nonmuscle Beta Actin Emdb Emd 27572 Arora As Huang Hl Heissler Sm Chinthalapudi K 2024 Cryo Em Structure, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. mary poppins disney plus hutchens chevy newport news vaWebbA smooth muscle antibody (SMA) is a type of antibody known as an autoantibody. Normally, your immune system makes antibodies to attack foreign substances like … mary poppins disneylandWebbSMC-specific marker genes including SM a-actin, SM myosin heavy chain, SM22, h-caldesmon, calponin, and telokin. The CArGs within any given SMC-specific promoter are … mary poppins disney screencapsWebb15 jan. 1992 · Addition of sequence between positions −151 and −257 (p257CAT) resulted in a 7-fold increase in chloramphenicol acetyltransferase activity over that of p151CAT in rat SMC, but not in chicken SMC. A genomic clone encoding the rat smooth muscle alpha-actin gene was isolated, and the 5'-flanking region was partially characterized. hutchens cleaners