WebH2AX and phospho-SMC1 foci in transgenic tissue. These findings suggest that Myc overexpression causes DNA damage in vivo and that the ATM-dependent response to this damage is critical for p53 activation, apoptosis, and the suppression of tumor development. p53 DNA damage T he c-myc oncogene is overexpressed in a large percentage of WebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved …
Anti-ATM (phospho Ser1981) antibody (GTX132146) GeneTex
WebJul 1, 2024 · The HMGB1 protein is found in the nucleus and cytoplasm, and is widely present in many organs and tissues, such as lymphoid tissue, lung, heart, spleen, brain, liver, and kidney. HMGB1 function usually depends on its location, context, and post-translational modification [23]. WebJul 31, 2024 · Ataxia telangiectasia mutated kinase (ATM) is a DNA damage response protein with a primary nuclear function to regulate cell cycle progression in response to … chirrupings meaning in hindi
Heart neurons use clock genes to control myocyte proliferation
WebPhospho-ATM (Ser367) Polyclonal Antibody detects endogenous levels of ATM only when phosphorylated at Ser367. Target Information Ataxia-telangiectasia Mutated (ATM) is a … WebJun 1, 2024 · The primary antibodies used were from Abcam: pATM (S 1981; ab81292), ATM (ab199726), pKAP1 (Ser 824; ab133440), KAP1 (ab22553), and Cell Signaling Technology: p-p53 (Ser 15; 9284S), p53 (48818S), pCHK2 (T68; 2197S), CHK2 (3440S), horseradish peroxidase–conjugated GAPDH (3683). Immunofluorescence studies WebUse Anti-phospho-ATM (Ser1981) Antibody, clone 10H11.E12 (Mouse Monoclonal Antibody) validated in ICC, IF, IP, WB to detect phospho-ATM (Ser1981) also known as A-T mutated. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References chirrupings