High mobility group protein hmg-i/hmg-y
WebHigh mobility group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. HMG-1 belongs to the high mobility group and contains a HMG-box domain. Function. WebJan 23, 2007 · High mobility group protein HMG-I/HMG-Y Short names HMG-I (Y) Alternative names High mobility group AT-hook protein 1 ( High mobility group protein A1) Gene names Name Hmga1 Organism names Organism Rattus norvegicus (Rat) Taxonomic identifier 10116 NCBI Taxonomic lineage
High mobility group protein hmg-i/hmg-y
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WebMar 6, 2014 · High mobility group (HMG) proteins are the most abundant non-histone chromatin associated proteins. Based on their DNA binding domains, the HMG proteins are subdivided into three families (Figure 1A ): HMGA (containing AT-hooks), HMGB (containing HMG-boxes) and HMGN (containing nucleosomal binding domains) ( Bustin, 2001; Catez … WebSep 1, 2008 · The high mobility group (HMG) proteins, including HMGA, HMGB and HMGN, are abundant and ubiquitous nuclear proteins that bind to DNA, nucleosome and other …
WebJan 23, 2007 · HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions. Features WebMar 5, 2002 · A 268 bp region (P268) of the pea plastocyanin gene promoter responsible for high‐level expression has been shown to interact with the high mobility group proteins …
WebThe HMG (high mobility group) proteins are transcription regulators. HMGAs bind to the AT-rich regions of the minor groove of the DNA. HMGA2 is overexpressed in some cancers. It regulates the cell cycle, activates epithelial mesenchymal transition (EMT) and promotes cancer invasion and metastasis. WebApr 9, 2024 · High Mobility Group A1 (HMGA1): Structure, Biological Function, and Therapeutic Potential. Prognostic Significance of HMGA1 Expression in Lung Cancer …
WebNov 13, 2013 · Friedmann et al. (1993) mapped the gene encoding high mobility group protein HMGIY to 6p23-p21 by analysis of hamster/human somatic cell hybrids and …
WebThe high mobility group I, Y, and I-C proteins are low-molecular-weight, nonhistone chromosomal proteins that play a general role modulating gene expression during … list stream findfirstWebhigh mobility group protein HMG-I/HMG-Y, high mobility group AT-hook protein 1, high mobility group protein GeneRIFs: Gene References Into Functions distinct loci exist for growth and fatness in the two populations and identified HMGA1 and PLAG1 as strong candidate genes on SSC7 and SSC4, respectively. impact national geographic learning• Hui H, Perfetti R (Feb 2002). "Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood". European Journal of Endocrinology. 146 (2): 129–41. doi:10.1530/eje.0.1460129. PMID 11834421. • Van Maele B, Debyser Z (2005). "HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins". AIDS Reviews. 7 (1): 26–43. PMID 15875659. list stream allmatchWebApr 23, 2024 · CHARLOTTE, N.C., April 23, 2024 – Atrium Health is pleased to announce that 36 former Holston Medical Group (HMG) physicians are joining the Atrium Health family … impact nation fellowship churchWebNov 27, 1992 · Abstract. In this paper, we show that both NF-κB and the high mobility group protein I (Y) (HMG I (Y)) are required for virus induction of the human interferon-β (IFN-β) … impact national insurance increase 2022WebHigh mobility group (HMG) proteins are an abundant class of chromosomal proteins facilitate assembly of higher order structures. The mammalian HMG proteins have been grouped into three distinct families on the basis of their characteristic functional sequence: the HMGB, the HMGN, and the HMGA family. The HMG proteins of Drosophila … impact nations globalWebThe HMGA (High Mobility Group A) protein family belongs to the same High Mobility Group superfamily of HMGN proteins . Despite distinct families differing in functions and structural domains, all HMG proteins lack any obvious specificity for DNA consensus sequences and compete with different mechanisms with histone H1 for DNA binding, thus ... impact nation fellowship