High affinity choline transporter 1-like

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August undefined, 2024

Web3.24.2.2.2 Choline transport and metabolism to phospholipids. The lifetime of choline in the blood and its distribution in the body, as well as its transport into the cells are critical steps in the metabolic fate of choline. There are several transporter genes encoding choline transporters (Michel et al., 2006 ): (1) The high-affinity choline ... Web29 de jul. de 2014 · The cho-1 was shown to be expressed in the cholinergic motor neurons of the ventral nerve cord in C. elegans supporting the idea that cho-1 encodes the high-affinity choline transporter . The DNA sequence of cho-1 enabled him to clone homologous cDNAs in rat and human being , which were termed as CHT1.

[PDF] Molecular properties of the high-affinity choline transporter ...

Web20 de set. de 2024 · Brain microvascular endothelial cells, which comprise part of the blood–brain barrier, take up extracellular choline via intermediate-affinity choline transporter-like protein 1 (CTL1) and low-affinity CTL2 transporters. WebGene ID: 104150095, updated on 24-Jan-2024. Summary Other designations. high affinity choline transporter 1-like, High affinity choline transporter 1, High affinity choline … how much is diesel per liter in south africa

Q9GZV3 - UniProt

Web31 de out. de 2000 · Here we report the molecular cloning and functional characterization of the human high-affinity choline transporter (hCHT1). The hCHT1 exhibits significant … WebA choline uptake system with a high affinity for choline has long been assumed to be present in cholinergic neurons. Very recently, the molecular entity for the high-affinity … how do bushfires start naturally

Choline transporter-like proteins 1 and 2 are newly identified …

Web10 de abr. de 2024 · Earlier, we showed that Agp2 regulates the expression of several genes of the high-affinity polyamine uptake pathway and these genes include SAM3 and DUR3 encoding the two high-affinity polyamine uptake transporters, SKY1 and PTK2 encoding kinases that regulate the high-affinity polyamine uptake process, as well as … Web8 de mar. de 2006 · Interestingly, mutation of this dileucine-like motif attenuates internalization of CHT1 and increases choline uptake similarly to over-expression of either dynamin I-K44A or AP180-C, suggesting that this motif is responsible for most, if not all, of the clathrin-mediated internalization of the high-affinity choline transporter (Ribeiro et … how do bushfires spreadWeb1 de jan. de 2024 · CHT1 has been functionally characterized by its capacity to transport choline with high affinity when expressed in cultured cells or Xenopus oocytes. CHT1 transports choline with a Km value of 1–5 μM in a Na + - and Cl −-dependent manner (Okuda et al. 2000).The only known specific inhibitor of CHT1 is hemicholinium-3 (HC-3), … how much is diesel tax in nz

"Web1 de jan. de 2024 · Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters. ... As further shown in Figure 2 C, Ctrl fibroblasts, high-affinity (K 1 = 66.5 ± 8.5 μM) and low-affinity (K 2 = 299.0 ± 13.1 μM) Etn bindings were similar to COS-7 cells bindings ... " - High affinity choline transporter 1-like

High affinity choline transporter 1-like

The “ins” and “outs” of the high‐affinity choline transporter ...

Web3 de nov. de 2000 · The presence of the high-affinity choline transporter Choline transporter 1 in nerve fibers and epithelial cells in the human and rat skin supporting the pivotal role of this transporter in both the neuronal and non-neuronal cholinergic system of the skin is shown. 47. PDF. View 3 excerpts, cites background. WebThe molecular entity for the high-affinity choline transporter was identified and is designated CHT1, which mediates Na+- and Cl−-dependent choline uptake with high sensitivity to hemicholinium-3 and has been characterized both at the molecular and functional levels. The cholinergic neurons have long been a model for biochemical …

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Web2 de abr. de 2012 · Choline transporter-like protein 1 (CTL1) and CTL2 mRNA were highly expressed, while mRNA for high-affinity choline transporter 1 (CHT1) and organic cation transporters ... Web1 de mai. de 2003 · High-affinity choline uptake (HACU) was one of the last features of cholinergic signaling to be defined at a molecular level, achieved through the cloning of …

WebHigh affinity choline transporter 1, Hemicholinium-3-sensitive choline transporter, CHT, Solute carrier family 5 member 7. eCl@ss: 32160702. NACRES: NA.41. Recommended Products. Slide 1 of 10. 1 of 10. Sigma-Aldrich. AV41516. Anti-SLC22A1 (AB1) antibody produced in rabbit. IgG fraction of antiserum. Webhigh-affinity glutamate and neutral amino acid transporter (SLC1A1, SLC1A2, SLC1A3, SLC1A4, SLC1A5, SLC1A6, SLC1A7) ... Choline-like transporter (SLC44A1, SLC44A2, SLC44A3, SLC44A4, SLC44A5) Putative sugar transporter (SLC45A1, SLC45A2, SLC45A3, SLC45A4) Folate transporter

WebLOC799259 high-affinity choline transporter 1-like [ (zebrafish)] Gene ID: 799259, updated on 4-Nov-2024. Web1 de out. de 2014 · A single nucleotide polymorphism (SNP) for human CHT1 has been identified, which has a replacement from isoleucine to valine in the third transmembrane segment and shows the choline uptake activity of 50-60% as much as that of wild-typeCHT1. This article summarizes molecular properties of the high-affinity choline …

WebCholine Transporter. Choline transporter-like proteins 1 (CDw92 is a C-terminal variant), 2 and 4 are expressed at the plasma membrane of neurons, endothelial cells, and …

Web8 de mar. de 2006 · Two transport activities for choline have been described in neurons: a ubiquitous, low-affinity, sodium-independent transport system that is inhibited by … how do bushfires start in australiaWebDOI: 10.1016/S0024-3205(03)00088-2 Corpus ID: 12543843; Expression of the high-affinity choline transporter CHT1 in epithelia. @article{Pfeil2003ExpressionOT, title={Expression of the high-affinity choline transporter CHT1 in epithelia.}, author={Uwe Pfeil and Rainer Viktor Haberberger and Katrin Susanne Lips and Lars Eberling and … how do bushfires workWebCHT1 protein is mainly found in intracellular organelles, such as endosomal compartments and synaptic vesicles. The presence of CHT1 at the plasma membrane is limited by … how much is diesel todayWebSLC44A1 is detected in both the plasma and mitochondrial membranes where the protein is able to transport choline at high affinity and in a Na(+)-independent manner. The … how much is diet chefWeb1 de abr. de 2013 · The Na +-independent, high affinity choline carrier system proposed to supply choline for the synthesis of cell membrane phospholipids was recently associated with SLC44 family members (SLC44A1-5) also called choline-like transporter family.SLC44A1 is widely expressed throughout the nervous system in both neurons and … how much is diet coke at costcoWebCholine transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters. Adrian Taylor. Adrian Taylor. ... high-affinity (K 1 = 66.5 ± 8.5 μM) and low-affinity (K 2 = 299.0 ± 13.1 μM) Etn bindings were similar to COS-7 cells bindings (K 1 = 55.6 ± 14.8 μM and K 2 = 277.3 ± 7.9 μM). how much is diet cokeWebThe high-affinity choline transporter: a critical protein for sustaining cholinergic signaling as revealed in studies of genetically altered mice Authors M H Bazalakova 1 , R D … how do business analysts add value